Frost & Sullivan Lauds Pressure BioSciences' Novel and Systematic Approach for the Detergent-free Extraction and Fractionation of Proteins from Lipid-rich Samples
Tuesday November 27, 11:22 am ET
PALO ALTO, Calif.--(BUSINESS WIRE)--Based on its recent analysis of the protein separation technologies market, Frost & Sullivan today announced that Pressure BioSciences, Inc. (NasdaqCM: PBIO) has been named the recipient of the 2007 North American Frost & Sullivan Award for Technology Innovation.
This Award recognizes Pressure BioSciences for its development of a new, cutting-edge sample preparation technology for tissue and cell disruption and for the development of a method for the detergent-free extraction of proteins from lipid rich tissues. This novel approach combines the power of the Company?s Pressure Cycling Technology (PCT) with the innovative chemistry of its ProteoSolve-LRS kit, resulting in higher protein recovery, enhanced reproducibility, and significant advantages in speed and handling.
?Protein expression from lipid rich tissues is crucial to understanding many disease states such as obesity, heart disease, diabetes, and certain cancer types, among others,? says Frost & Sullivan Senior Research Analyst Sandhya Kamath. ?As a result, sample preparation is drawing attention in proteomic studies since it can affect the accuracy and the overall quality of the downstream analytical processes.?
For instance, conventional detergent-based methods used to extract proteins from tissues produce highly variable results. This increases the processing time for protein extraction as well as the costs, compromising the quantity and quality of the extracted proteins.
Pressure BioSciences offers an automated method of protein extraction that allows for optimal protein recovery.
?Unlike conventional methods of tissue delipidation that comprise several stages such as cell and tissue disruption, protein extraction from lipids, and partitioning, the new PCT-dependent sample preparation approach from Pressure BioSciences combines these complex stages into a single step, as a result of which the fractions of proteins and lipids generated from each sample can be analyzed individually, faster, more efficiently, and with more reproducibility,? notes Kamath. ?Moreover, this approach integrates PCT and reagents to extract and fractionate proteins from lipid-rich tissues in a detergent-free manner.?
Pressure BioSciences? PCT technology can be applied across genomic and proteomic sample preparation, enzyme control, pathogen inactivation, immunodiagnostics, and protein purification.
To enhance the proof of concept, scientists at Pressure BioSciences collaborated with researchers at the Harvard School of Public Health to carry out a research study on the comparative proteomic analysis of adipose tissue isolated from genetically different animal lines.
The study exposed differences in protein expression that could be the base for newer research in mechanistic studies of obesity and Type 2 diabetes. The firm?s researchers are also working to widen the scope of pressure-driven liquid-liquid extraction in biological samples.
In recognition of Pressure BioSciences? commendable innovation and the resulting technology advancement in the extraction and fractionation of proteins, Frost & Sullivan proudly presents it with the 2007 Award for Technology Innovation.
Each year, Frost & Sullivan presents this Award to the company that has demonstrated excellence in new products and technologies within their industry. The Award recognizes innovation through the launch of a broad line of emerging products and technologies.
Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research in order to identify best practices in the industry.
About Pressure BioSciences
Pressure BioSciences, Inc. (PBI) is a publicly traded company focused on the development of a novel, enabling technology called pressure cycling technology (PCT). PCT uses cycles of hydrostatic pressure between ambient and ultra-high levels (up to 35,000 psi and greater) to control bio-molecular interactions. PBI currently holds 13 US and 6 foreign patents covering multiple applications of PCT in the life sciences field, including in such areas as genomic and proteomic sample preparation, pathogen inactivation, the control of chemical reactions, immunodiagnostics, and protein purification.
About Frost & Sullivan
Frost & Sullivan, the Growth Consulting Company, partners with clients to accelerate their growth. The company's Growth Partnership Services, Growth Consulting and Career Best Practices empower clients to create a growth focused culture that generates, evaluates and implements effective growth strategies. Frost & Sullivan employs over 45 years of experience in partnering with Global 1000 companies, emerging businesses and the investment community from more than 30 offices on six continents. For more information, visit http://www.awards.frost.com.
For Further Information, Contact:
RedChip Companies, Inc.
500 Winderley Place, Suite 100, Orlando, FL 32751, (800) 733-2447,
Fax: (407) 644-0758, info@redchip.com
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